Version 5.4
Bos taurus Gene: ESD
Summary
InnateDB Gene IDBG-629030.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ESD
Gene Name S-formylglutathione hydrolase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000003415
Encoded Proteins
IDBP-680425
S-formylglutathione hydrolase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139684:
This gene encodes a serine hydrolase that belongs to the esterase D family. The encoded enzyme is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of sialic acids. This gene is used as a genetic marker for retinoblastoma and Wilson's disease. [provided by RefSeq, Feb 2009]
This gene encodes a serine hydrolase that belongs to the esterase D family. The encoded enzyme is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of sialic acids. This gene is used as a genetic marker for retinoblastoma and Wilson\'s disease. [provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:16771120-16788845
Strand Reverse strand
Band
Transcripts
ENSBTAT00000004431 ENSBTAP00000004431
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008236 serine-type peptidase activity
GO:0016787 hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0018738 S-formylglutathione hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0046294 formaldehyde catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0031410 cytoplasmic vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000139684
View Gene Order
ENSMUSG00000021996
View Gene Order
Cross-References
SwissProt Q08E20
TrEMBL
UniProt Splice Variant
Entrez Gene 535653
UniGene Bt.61889
RefSeq NM_001076065 XM_005213659 XM_005213660 XM_005213661 XM_005213662
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123461
GenPept AAI23462
RNA Seq Atlas 535653

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca