Version 5.4
Mus musculus Gene: Rragb
Summary
InnateDB Gene IDBG-180683.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rragb
Gene Name Ras-related GTP binding B
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000041658
Encoded Proteins
IDBP-180685
Ras-related GTP binding B
IDBP-625926
Ras-related GTP binding B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000083750:
Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:153139981-153171943
Strand Forward strand
Band F3
Transcripts
ENSMUST00000039720 ENSMUSP00000039013
ENSMUST00000144175 ENSMUSP00000134162
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0032561 guanyl ribonucleotide binding
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0032008 positive regulation of TOR signaling
GO:0034613 cellular protein localization
GO:0071230 cellular response to amino acid stimulus
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005794 Golgi apparatus
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000083750
View Gene Order
ENSBTAG00000012980
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04150
mTOR signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04150
mTOR signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q6NTA4
TrEMBL G3UYP1
UniProt Splice Variant
Entrez Gene 245670
UniGene Mm.190922
RefSeq NM_001004154
OMIM
CCDS CCDS30480
HPRD
IMGT
MGI ID MGI:3038613
MGI Symbol Rragb
EMBL AL672293 BC069180 BC070407
GenPept AAH69180 AAH70407 CAM16638
RNA Seq Atlas 245670

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca