Mus musculus Gene: Ddx23
Summary
InnateDB Gene IDBG-180785.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ddx23
Gene Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
Synonyms 3110082M05Rik; 4921506D17Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000003360
Encoded Proteins
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174243:
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:98645134-98662889
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000003450 ENSMUSP00000003450
ENSMUST00000160506
ENSMUST00000159423
ENSMUST00000161030
ENSMUST00000162384 ENSMUSP00000125168
ENSMUST00000159170
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
Predicted by orthology
Total 29 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006200 ATP catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005682 U5 snRNP
GO:0005739 mitochondrion
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Spliceosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
mRNA Splicing - Major Pathway pathway
mRNA Splicing - Minor Pathway pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
mRNA Splicing pathway
Gene Expression pathway
KEGG
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.45725 Mm.459538
RefSeq NM_001080981 XM_006521493
OMIM
CCDS CCDS37193
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas