InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Hnrnpf

Summary

InnateDB Gene

IDBG-181206.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hnrnpf

Gene Name

heterogeneous nuclear ribonucleoprotein F

Synonyms

4833420I20Rik; AA407306; Hnrpf

Species

Mus musculus

Ensembl Gene

ENSMUSG00000042079

Encoded Proteins

IDBP-181208

heterogeneous nuclear ribonucleoprotein F

IDBP-627323

heterogeneous nuclear ribonucleoprotein F

IDBP-627326

heterogeneous nuclear ribonucleoprotein F

IDBP-714926

IDBP-714519

IDBP-714848

IDBP-714681

IDBP-715850

IDBP-715065

IDBP-715289

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169813:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:117900324-117925622

Strand

Forward strand

Band

Transcripts

ENSMUST00000035493	ENSMUSP00000045048
ENSMUST00000167182	ENSMUSP00000126817
ENSMUST00000163168	ENSMUSP00000130023
ENSMUST00000179478	ENSMUSP00000136436
ENSMUST00000177570	ENSMUSP00000136162
ENSMUST00000177743	ENSMUSP00000136477
ENSMUST00000179224	ENSMUSP00000136751
ENSMUST00000180020	ENSMUSP00000137632
ENSMUST00000177918	ENSMUSP00000137091
ENSMUST00000180341	ENSMUSP00000136700

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 82 interaction(s) predicted by orthology.

Experimentally validated
Total	18 [view]
Protein-Protein	18 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	82 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003727	single-stranded RNA binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding