Version 5.4
Mus musculus Gene: Cnot6l
Summary
InnateDB Gene IDBG-181254.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cnot6l
Gene Name CCR4-NOT transcription complex, subunit 6-like
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000034724
Encoded Proteins
IDBP-181258
CCR4-NOT transcription complex, subunit 6-like
IDBP-254781
CCR4-NOT transcription complex, subunit 6-like
IDBP-400537
CCR4-NOT transcription complex, subunit 6-like
IDBP-534226
CCR4-NOT transcription complex, subunit 6-like
IDBP-532113
CCR4-NOT transcription complex, subunit 6-like
IDBP-540457
CCR4-NOT transcription complex, subunit 6-like
IDBP-532478
CCR4-NOT transcription complex, subunit 6-like
IDBP-532107
CCR4-NOT transcription complex, subunit 6-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138767:
Gene Information
Type Protein coding
Genomic Location Chromosome 5:96070333-96164171
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000036646 ENSMUSP00000047522
ENSMUST00000113005 ENSMUSP00000108629
ENSMUST00000122003 ENSMUSP00000113821
ENSMUST00000155901 ENSMUSP00000119415
ENSMUST00000152490
ENSMUST00000137066
ENSMUST00000129646 ENSMUSP00000123653
ENSMUST00000141383 ENSMUSP00000114436
ENSMUST00000137207 ENSMUSP00000121627
ENSMUST00000154500 ENSMUSP00000116326
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004535 poly(A)-specific ribonuclease activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006397 mRNA processing
GO:0006417 regulation of translation
GO:0008284 positive regulation of cell proliferation
GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly
GO:0031047 gene silencing by RNA
GO:0061157 mRNA destabilization
GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030014 CCR4-NOT complex
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000138767
View Gene Order
Pathways
NETPATH
REACTOME
REACT_244119
Deadenylation of mRNA pathway
REACT_233572
Gene Expression pathway
REACT_235784
Deadenylation-dependent mRNA decay pathway
KEGG
mmu03018
RNA degradation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20514
Deadenylation of mRNA pathway
REACT_20639
Deadenylation-dependent mRNA decay pathway
REACT_71
Gene Expression pathway
KEGG
hsa03018
RNA degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D3YVH6 D3Z2G5
UniProt Splice Variant
Entrez Gene 231464
UniGene Mm.384746 Mm.411687 Mm.412929 Mm.465960 Mm.473459
RefSeq NM_001285511 NM_001285514 NM_144910 NM_178854 XM_006534870 XM_006534871 XM_006534872
OMIM
CCDS CCDS19448 CCDS51566
HPRD
IMGT
MGI ID MGI:2443154
MGI Symbol Cnot6l
EMBL AC129600 AC149285
GenPept
RNA Seq Atlas 231464

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca