Version 5.4
Homo sapiens Gene: CNOT6L
Summary
InnateDB Gene IDBG-25831.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CNOT6L
Gene Name CCR4-NOT transcription complex, subunit 6-like
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000138767
Encoded Proteins
IDBP-474033
CCR4-NOT transcription complex, subunit 6-like
IDBP-479081
CCR4-NOT transcription complex, subunit 6-like
IDBP-481823
CCR4-NOT transcription complex, subunit 6-like
IDBP-475101
CCR4-NOT transcription complex, subunit 6-like
IDBP-481051
CCR4-NOT transcription complex, subunit 6-like
IDBP-482781
CCR4-NOT transcription complex, subunit 6-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:77713387-77819615
Strand Reverse strand
Band q21.1
Transcripts
ENST00000504123 ENSP00000424896
ENST00000515506 ENSP00000423750
ENST00000512485 ENSP00000425571
ENST00000504804 ENSP00000425836
ENST00000505983 ENSP00000426320
ENST00000508371
ENST00000506166
ENST00000515441 ENSP00000426269
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 23 [view]
Protein-Protein 23 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004535 poly(A)-specific ribonuclease activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006417 regulation of translation
GO:0008284 positive regulation of cell proliferation
GO:0010467 gene expression
GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
GO:0031047 gene silencing by RNA
GO:0061157 mRNA destabilization
GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0030014 CCR4-NOT complex
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000034724
View Gene Order
Pathways
NETPATH
REACTOME
REACT_20514
Deadenylation of mRNA pathway
REACT_20639
Deadenylation-dependent mRNA decay pathway
REACT_71
Gene Expression pathway
KEGG
hsa03018
RNA degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.531161 Hs.592519 Hs.598889 Hs.604563 Hs.714958
RefSeq NM_001286790 NM_144571 XM_005262877
HUGO
OMIM
CCDS CCDS68731
HPRD 10841
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca