Version 5.4
Mus musculus Gene: Zfp57
Summary
InnateDB Gene IDBG-182059.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zfp57
Gene Name zinc finger protein 57
Synonyms G19; Zfp-57
Species Mus musculus
Ensembl Gene ENSMUSG00000036036
Encoded Proteins
IDBP-182061
zinc finger protein 57
IDBP-182063
zinc finger protein 57
IDBP-622212
zinc finger protein 57
IDBP-622215
zinc finger protein 57
IDBP-714490
IDBP-622218
zinc finger protein 57
IDBP-622220
zinc finger protein 57
IDBP-622221
zinc finger protein 57
IDBP-622222
zinc finger protein 57
IDBP-622223
zinc finger protein 57
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204644:
The protein encoded by this gene is a zinc finger protein containing a KRAB domain. Studies in mouse suggest that this protein may function as a transcriptional repressor. Mutations in this gene have been associated with transient neonatal diabetes mellitus type 1 (TNDM1).[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:37001163-37010635
Strand Forward strand
Band B1
Transcripts
ENSMUST00000069250 ENSMUSP00000065811
ENSMUST00000089968 ENSMUSP00000087414
ENSMUST00000172527 ENSMUSP00000134116
ENSMUST00000174747 ENSMUSP00000133460
ENSMUST00000174016
ENSMUST00000174470
ENSMUST00000173588 ENSMUSP00000135655
ENSMUST00000173921 ENSMUSP00000133582
ENSMUST00000172580 ENSMUSP00000133894
ENSMUST00000174524 ENSMUSP00000134418
ENSMUST00000174672 ENSMUSP00000133821
ENSMUST00000172540 ENSMUSP00000134024
ENSMUST00000172502
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006349 regulation of gene expression by genetic imprinting
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007422 peripheral nervous system development
GO:0043045 DNA methylation involved in embryo development
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005720 nuclear heterochromatin
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000204644
View Gene Order
ENSBTAG00000017836
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 22715
UniGene Mm.305561 Mm.392546
RefSeq NM_001013745 NM_001168501 NM_001168502 XM_006524223 XM_006524225 XM_006536599 XM_006536837 XM_006536838 XM_006536840 XM_006536841 XM_006537330 XM_006537332 XM_006537333
OMIM
CCDS CCDS28733 CCDS50106
HPRD
IMGT
MGI ID MGI:99204
MGI Symbol Zfp57
EMBL
GenPept
RNA Seq Atlas 22715

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca