Mus musculus Gene: Ccnb2
Summary
InnateDB Gene IDBG-182158.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ccnb2
Gene Name cyclin B2
Synonyms CycB2
Species Mus musculus
Ensembl Gene ENSMUSG00000032218
Encoded Proteins
cyclin B2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157456:
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:70407689-70421554
Strand Reverse strand
Band D
Transcripts
ENSMUST00000034742 ENSMUSP00000034742
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019901 protein kinase binding
Biological Process
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0001701 in utero embryonic development
GO:0007067 mitotic nuclear division
GO:0040007 growth
GO:0043029 T cell homeostasis
GO:0048538 thymus development
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005813 centrosome
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Activation of NIMA Kinases NEK9, NEK6, NEK7 pathway
Nuclear Envelope Breakdown pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Nuclear Pore Complex (NPC) Disassembly pathway
Resolution of Sister Chromatid Cohesion pathway
Cell Cycle pathway
M Phase pathway
Cell Cycle Checkpoints pathway
G2/M Checkpoints pathway
Mitotic G2-G2/M phases pathway
Golgi Cisternae Pericentriolar Stack Reorganization pathway
Mitotic Prometaphase pathway
Cyclin A/B1 associated events during G2/M transition pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Condensation of Prometaphase Chromosomes pathway
Cyclin B2 mediated events pathway
Mitotic Prophase pathway
G2/M DNA replication checkpoint pathway
KEGG
p53 signaling pathway pathway
Cell cycle pathway
Progesterone-mediated oocyte maturation pathway
Oocyte meiosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
TGF_beta_Receptor pathway
REACTOME
G2/M DNA replication checkpoint pathway
Golgi Cisternae Pericentriolar Stack Reorganization pathway
Activation of NIMA Kinases NEK9, NEK6, NEK7 pathway
Condensation of Prometaphase Chromosomes pathway
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Polo-like kinase mediated events pathway
Cyclin A/B1 associated events during G2/M transition pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Cyclin B2 mediated events pathway
G2/M Checkpoints pathway
Nuclear Pore Complex (NPC) Disassembly pathway
Cell Cycle pathway
M Phase pathway
G2/M Transition pathway
Mitotic Prophase pathway
Cell Cycle, Mitotic pathway
Mitotic G2-G2/M phases pathway
Nuclear Envelope Breakdown pathway
Cell Cycle Checkpoints pathway
G2/M Transition pathway
Cyclin A/B1 associated events during G2/M transition pathway
M Phase pathway
Nuclear Pore Complex (NPC) Disassembly pathway
Nuclear Envelope Breakdown pathway
G2/M DNA replication checkpoint pathway
Condensation of Prometaphase Chromosomes pathway
Cell Cycle, Mitotic pathway
Mitotic G2-G2/M phases pathway
Cell Cycle pathway
Activation of NIMA Kinases NEK9, NEK6, NEK7 pathway
Golgi Cisternae Pericentriolar Stack Reorganization pathway
Cyclin B2 mediated events pathway
Mitotic Prophase pathway
G2/M Checkpoints pathway
Resolution of Sister Chromatid Cohesion pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Mitotic Prometaphase pathway
Cell Cycle Checkpoints pathway
KEGG
Cell cycle pathway
p53 signaling pathway pathway
Progesterone-mediated oocyte maturation pathway
Oocyte meiosis pathway
INOH
PID NCI
Validated transcriptional targets of deltaNp63 isoforms
FOXM1 transcription factor network
Cross-References
SwissProt P30276
TrEMBL
UniProt Splice Variant
Entrez Gene 12442
UniGene
RefSeq NM_007630
OMIM
CCDS CCDS23320
HPRD
IMGT
MGI ID MGI:88311
MGI Symbol Ccnb2
EMBL AK076122 BC008247 CH466522 CT010286 X66032
GenPept AAH08247 BAC36200 CAA46831 CAJ18494 EDL26195
RNA Seq Atlas 12442