Version 5.4
| Bos taurus Gene: CCNB2 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-646587.3 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | CCNB2 | ||||||||||||||||||
| Gene Name | G2/mitotic-specific cyclin-B2 | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Bos taurus | ||||||||||||||||||
| Ensembl Gene | ENSBTAG00000005269 | ||||||||||||||||||
| Encoded Proteins |
G2/mitotic-specific cyclin-B2
G2/mitotic-specific cyclin-B2
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157456:
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 10:51247755-51272733 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | |||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
G2/M Transition pathway
Cyclin A/B1 associated events during G2/M transition pathway
M Phase pathway
Nuclear Pore Complex (NPC) Disassembly pathway
Nuclear Envelope Breakdown pathway
G2/M DNA replication checkpoint pathway
Condensation of Prometaphase Chromosomes pathway
Cell Cycle, Mitotic pathway
Mitotic G2-G2/M phases pathway
Cell Cycle pathway
Activation of NIMA Kinases NEK9, NEK6, NEK7 pathway
Golgi Cisternae Pericentriolar Stack Reorganization pathway
Cyclin B2 mediated events pathway
Mitotic Prophase pathway
G2/M Checkpoints pathway
Resolution of Sister Chromatid Cohesion pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Mitotic Prometaphase pathway
Cell Cycle Checkpoints pathway
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| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||
| NETPATH |
TGF_beta_Receptor pathway
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| REACTOME |
G2/M DNA replication checkpoint pathway
Golgi Cisternae Pericentriolar Stack Reorganization pathway
Activation of NIMA Kinases NEK9, NEK6, NEK7 pathway
Condensation of Prometaphase Chromosomes pathway
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Polo-like kinase mediated events pathway
Cyclin A/B1 associated events during G2/M transition pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Cyclin B2 mediated events pathway
G2/M Checkpoints pathway
Nuclear Pore Complex (NPC) Disassembly pathway
Cell Cycle pathway
M Phase pathway
G2/M Transition pathway
Mitotic Prophase pathway
Cell Cycle, Mitotic pathway
Mitotic G2-G2/M phases pathway
Nuclear Envelope Breakdown pathway
Cell Cycle Checkpoints pathway
Activation of NIMA Kinases NEK9, NEK6, NEK7 pathway
Nuclear Envelope Breakdown pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Nuclear Pore Complex (NPC) Disassembly pathway
Resolution of Sister Chromatid Cohesion pathway
Cell Cycle pathway
M Phase pathway
Cell Cycle Checkpoints pathway
G2/M Checkpoints pathway
Mitotic G2-G2/M phases pathway
Golgi Cisternae Pericentriolar Stack Reorganization pathway
Mitotic Prometaphase pathway
Cyclin A/B1 associated events during G2/M transition pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Condensation of Prometaphase Chromosomes pathway
Cyclin B2 mediated events pathway
Mitotic Prophase pathway
G2/M DNA replication checkpoint pathway
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| KEGG |
Cell cycle pathway
p53 signaling pathway pathway
Progesterone-mediated oocyte maturation pathway
Oocyte meiosis pathway
p53 signaling pathway pathway
Cell cycle pathway
Progesterone-mediated oocyte maturation pathway
Oocyte meiosis pathway
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| INOH | |||||||||||||||||||
| PID NCI |
Validated transcriptional targets of deltaNp63 isoforms
FOXM1 transcription factor network
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| Cross-References | |||||||||||||||||||
| SwissProt | O77689 | ||||||||||||||||||
| TrEMBL | Q58D97 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 281668 | ||||||||||||||||||
| UniGene | Bt.41 | ||||||||||||||||||
| RefSeq | NM_174264 | ||||||||||||||||||
| HUGO | |||||||||||||||||||
| OMIM | |||||||||||||||||||
| CCDS | |||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AF080219 BC118382 BT020648 BT020669 BT020762 BT020822 BT021153 BT021700 DAAA02028814 DAAA02028815 | ||||||||||||||||||
| GenPept | AAC31953 AAI18383 AAX08665 AAX08686 AAX08779 AAX08839 AAX31335 AAX46547 | ||||||||||||||||||
| RNA Seq Atlas | 281668 | ||||||||||||||||||