Version 5.4
Homo sapiens Gene: CLEC12A
Summary
InnateDB Gene IDBG-18239.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLEC12A
Gene Name C-type lectin domain family 12, member A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000172322
Encoded Proteins
IDBP-18241
C-type lectin domain family 12, member A
IDBP-18243
C-type lectin domain family 12, member A
IDBP-18245
C-type lectin domain family 12, member A
IDBP-237346
C-type lectin domain family 12, member A
IDBP-387374
C-type lectin domain family 12, member A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:9951316-9995694
Strand Forward strand
Band p13.31
Transcripts
ENST00000355690 ENSP00000347916
ENST00000304361 ENSP00000302804
ENST00000350667 ENSP00000345448
ENST00000396507 ENSP00000379764
ENST00000449959
ENST00000434319 ENSP00000405244
ENST00000543839
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0030246 carbohydrate binding
Biological Process
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000053063
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.190519
RefSeq NM_001207010 NM_001300730 NM_138337 NM_201623 XM_005253324 XM_006719033 XM_006719034 XM_006719036 XM_006719037
HUGO
OMIM
CCDS CCDS55803 CCDS73442 CCDS8608 CCDS8609
HPRD 14719
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca