Version 5.4
Mus musculus Gene: Rasgef1b
Summary
InnateDB Gene IDBG-182542.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rasgef1b
Gene Name RasGEF domain family, member 1B
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000029333
Encoded Proteins
IDBP-182544
RasGEF domain family, member 1B
IDBP-625910
RasGEF domain family, member 1B
IDBP-625911
RasGEF domain family, member 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 20090772
[Homo sapiens] RASGEF1B is a guanine-nucleotide exchange factor (GEF), whose expression is induced in macrophages on stimulation with toll-like receptor (TLR) agonists.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138670:
Gene Information
Type Protein coding
Genomic Location Chromosome 5:99217426-99252927
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000031276 ENSMUSP00000031276
ENSMUST00000168092 ENSMUSP00000129652
ENSMUST00000166484 ENSMUSP00000128947
ENSMUST00000166632
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0032318 regulation of Ras GTPase activity
GO:0032320 positive regulation of Ras GTPase activity
GO:0043087 regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005769 early endosome
GO:0005770 late endosome
GO:0030496 midbody
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000138670
View Gene Order
ENSBTAG00000006561
Not yet available
Cross-References
SwissProt Q8JZL7
TrEMBL
UniProt Splice Variant
Entrez Gene 320292
UniGene Mm.259074 Mm.471414
RefSeq NM_145839 XM_006534983 XM_006534985 NM_181318 XM_006534984
OMIM
CCDS CCDS39179 CCDS51570
HPRD
IMGT
MGI ID MGI:2443755
MGI Symbol Rasgef1b
EMBL AK028756 AK149812 AY129963 AY129964 BC050858 BC052726
GenPept AAH50858 AAH52726 AAM77973 AAM77974 BAC26101 BAE29099
RNA Seq Atlas 320292

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca