Version 5.4
Bos taurus Gene: RASGEF1B
Summary
InnateDB Gene IDBG-643174.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RASGEF1B
Gene Name Ras-GEF domain-containing family member 1B
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006561
Encoded Proteins
IDBP-695716
Ras-GEF domain-containing family member 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 20090772
[Homo sapiens] RASGEF1B is a guanine-nucleotide exchange factor (GEF), whose expression is induced in macrophages on stimulation with toll-like receptor (TLR) agonists.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138670:
Gene Information
Type Protein coding
Genomic Location Chromosome 6:97988424-98026691
Strand Reverse strand
Band
Transcripts
ENSBTAT00000045329 ENSBTAP00000042728
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0032320 positive regulation of Ras GTPase activity
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005768 endosome
GO:0005769 early endosome
GO:0005770 late endosome
GO:0030496 midbody
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000138670
View Gene Order
ENSMUSG00000029333
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.6800
RefSeq NM_001083649 XM_005208141 XM_005208142 XM_005208143
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca