Version 5.4
Mus musculus Gene: Lin54
Summary
InnateDB Gene IDBG-183167.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lin54
Gene Name lin-54 homolog (C. elegans)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000035310
Encoded Proteins
IDBP-183169
lin-54 homolog (C. elegans)
IDBP-536820
lin-54 homolog (C. elegans)
IDBP-538306
lin-54 homolog (C. elegans)
IDBP-538490
lin-54 homolog (C. elegans)
IDBP-536468
lin-54 homolog (C. elegans)
IDBP-537560
lin-54 homolog (C. elegans)
IDBP-540043
lin-54 homolog (C. elegans)
IDBP-538549
lin-54 homolog (C. elegans)
IDBP-535543
lin-54 homolog (C. elegans)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000189308:
LIN54 is a component of the LIN, or DREAM, complex, an essential regulator of cell cycle genes (Schmit et al., 2009 [PubMed 19725879]).[supplied by OMIM, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:100441918-100500639
Strand Reverse strand
Band E4
Transcripts
ENSMUST00000046154 ENSMUSP00000041374
ENSMUST00000149714 ENSMUSP00000123544
ENSMUST00000137750 ENSMUSP00000120644
ENSMUST00000154921 ENSMUSP00000121137
ENSMUST00000123572 ENSMUSP00000123425
ENSMUST00000144030 ENSMUSP00000120010
ENSMUST00000152387 ENSMUSP00000121902
ENSMUST00000139234 ENSMUSP00000119322
ENSMUST00000134439 ENSMUSP00000118673
ENSMUST00000144716
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007049 cell cycle
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000189308
View Gene Order
ENSBTAG00000010546
Not yet available
Pathways
NETPATH
REACTOME
REACT_249770
Cell Cycle, Mitotic pathway
REACT_199110
G0 and Early G1 pathway
REACT_188804
Cell Cycle pathway
REACT_250573
Mitotic G1-G1/S phases pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_111214
G0 and Early G1 pathway
REACT_1006
Polo-like kinase mediated events pathway
REACT_21267
Mitotic G1-G1/S phases pathway
REACT_115566
Cell Cycle pathway
REACT_2203
G2/M Transition pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_21391
Mitotic G2-G2/M phases pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.212568 Mm.398513
RefSeq NM_001115010 NM_172714 XM_006534882 XM_006534883 XM_006534884 XM_006534885 XM_006534886
OMIM
CCDS CCDS19462
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca