InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Nckap1

Summary

InnateDB Gene

IDBG-183835.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nckap1

Gene Name

NCK-associated protein 1

Synonyms

C79304; H19; Hem-2; Hem2; mh19; mKIAA0587; Nap1; p125Nap1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000027002

Encoded Proteins

IDBP-183837

NCK-associated protein 1

IDBP-257433

NCK-associated protein 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000061676:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:80500512-80581380

Strand

Reverse strand

Band

Transcripts

ENSMUST00000028386	ENSMUSP00000028386
ENSMUST00000111760	ENSMUSP00000107390
ENSMUST00000154793
ENSMUST00000131872
ENSMUST00000134587

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Experimentally validated
Total	12 [view]
Protein-Protein	11 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0032403	protein complex binding
GO:0048365	Rac GTPase binding

Biological Process

GO:0001701	in utero embryonic development
GO:0001756	somitogenesis
GO:0001843	neural tube closure
GO:0007354	zygotic determination of anterior/posterior axis, embryo
GO:0007492	endoderm development
GO:0008078	mesodermal cell migration
GO:0010172	embryonic body morphogenesis
GO:0010592	positive regulation of lamellipodium assembly
GO:0016601	Rac protein signal transduction
GO:0030032	lamellipodium assembly
GO:0030903	notochord development
GO:0030950	establishment or maintenance of actin cytoskeleton polarity
GO:0032880	regulation of protein localization
GO:0035050	embryonic heart tube development
GO:0042074	cell migration involved in gastrulation
GO:0045175	basal protein localization
GO:0045176	apical protein localization
GO:0048339	paraxial mesoderm development
GO:0048340	paraxial mesoderm morphogenesis
GO:0048570	notochord morphogenesis
GO:0048617	embryonic foregut morphogenesis
GO:0050821	protein stabilization
GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation

Cellular Component

GO:0005737	cytoplasm
GO:0016021	integral component of membrane
GO:0030027	lamellipodium
GO:0031209	SCAR complex
GO:0031258	lamellipodium membrane
GO:0070062	extracellular vesicular exosome