Version 5.4
Mus musculus Gene: Tuba8
Summary
InnateDB Gene IDBG-184355.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tuba8
Gene Name tubulin, alpha 8
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000030137
Encoded Proteins
IDBP-184357
tubulin, alpha 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000183785:
This gene encodes a member of the alpha tubulin protein family. Alpha tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene are associated with polymicrogyria and optic nerve hypoplasia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:121210734-121226854
Strand Forward strand
Band F1
Transcripts
ENSMUST00000032233 ENSMUSP00000032233
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0006184 GTP catabolic process
GO:0051258 protein polymerization
Cellular Component
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0043234 protein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000183785
View Gene Order
ENSBTAG00000018530
Not yet available
Pathways
NETPATH
REACTOME
REACT_209837
Membrane Trafficking pathway
REACT_199054
Translocation of GLUT4 to the plasma membrane pathway
KEGG
mmu04540
Gap junction pathway
mmu04145
Phagosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa05130
Pathogenic Escherichia coli infection pathway
hsa04540
Gap junction pathway
hsa04145
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt Q9JJZ2
TrEMBL
UniProt Splice Variant
Entrez Gene 53857
UniGene Mm.32884
RefSeq NM_017379
OMIM
CCDS CCDS39615
HPRD
IMGT
MGI ID MGI:1858225
MGI Symbol Tuba8
EMBL AJ245923 AK009439 BC017631 CH466523 GU591980
GenPept AAH17631 ADD82895 BAB26288 CAB88033 EDK99659
RNA Seq Atlas 53857

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca