Version 5.4
Mus musculus Gene: Uchl3
Summary
InnateDB Gene IDBG-184380.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Uchl3
Gene Name ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000022111
Encoded Proteins
IDBP-184384
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000118939:
The protein encoded by this gene is a member of the deubiquitinating enzyme family. Members of this family are proteases that catalyze the removal of ubiquitin from polypeptides and are divided into five classes, depending on the mechanism of catalysis. This protein may hydrolyze the ubiquitinyl-N-epsilon amide bond of ubiquitinated proteins to regenerate ubiquitin for another catalytic cycle. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:101653967-101696124
Strand Forward strand
Band E2.3
Transcripts
ENSMUST00000002289 ENSMUSP00000002289
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 53 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 53 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004843 ubiquitin-specific protease activity
GO:0008233 peptidase activity
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007628 adult walking behavior
GO:0016579 protein deubiquitination
GO:0030163 protein catabolic process
GO:0032869 cellular response to insulin stimulus
GO:0042755 eating behavior
GO:0045600 positive regulation of fat cell differentiation
GO:0060041 retina development in camera-type eye
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000118939
View Gene Order
ENSBTAG00000008024
Not yet available
Cross-References
SwissProt Q9JKB1
TrEMBL
UniProt Splice Variant
Entrez Gene 50933
UniGene
RefSeq NM_016723
OMIM
CCDS CCDS27313
HPRD
IMGT
MGI ID MGI:1355274
MGI Symbol Uchl3
EMBL AB033370 AF247358 BC048481
GenPept AAF64193 AAH48481 BAB20094
RNA Seq Atlas 50933

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca