Version 5.4
Mus musculus Gene: Egfl6
Summary
InnateDB Gene IDBG-185395.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Egfl6
Gene Name EGF-like-domain, multiple 6
Synonyms Maeg
Species Mus musculus
Ensembl Gene ENSMUSG00000000402
Encoded Proteins
IDBP-185397
EGF-like-domain, multiple 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198759:
This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:166523007-166585720
Strand Reverse strand
Band F5
Transcripts
ENSMUST00000000412 ENSMUSP00000000412
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0007275 multicellular organismal development
GO:0010811 positive regulation of cell-substrate adhesion
GO:0030154 cell differentiation
GO:0030198 extracellular matrix organization
Cellular Component
GO:0005604 basement membrane
GO:0016020 membrane
GO:0031012 extracellular matrix
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000198759
View Gene Order
ENSBTAG00000017927
Not yet available
Cross-References
SwissProt Q9JJZ5
TrEMBL
UniProt Splice Variant
Entrez Gene 54156
UniGene Mm.37707
RefSeq NM_019397
OMIM
CCDS CCDS30528
HPRD
IMGT
MGI ID MGI:1858599
MGI Symbol Egfl6
EMBL AJ245672 AK053738 AL672174 BC117702
GenPept AAI17703 BAC35499 CAB92138 CAM23572
RNA Seq Atlas 54156

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca