Version 5.4
Homo sapiens Gene: NEDD1
Summary
InnateDB Gene IDBG-52158.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NEDD1
Gene Name neural precursor cell expressed, developmentally down-regulated 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000139350
Encoded Proteins
IDBP-52160
neural precursor cell expressed, developmentally down-regulated 1
IDBP-381437
neural precursor cell expressed, developmentally down-regulated 1
IDBP-381438
neural precursor cell expressed, developmentally down-regulated 1
IDBP-381440
neural precursor cell expressed, developmentally down-regulated 1
IDBP-596700
neural precursor cell expressed, developmentally down-regulated 1
IDBP-591100
neural precursor cell expressed, developmentally down-regulated 1
IDBP-598006
neural precursor cell expressed, developmentally down-regulated 1
IDBP-587474
neural precursor cell expressed, developmentally down-regulated 1
IDBP-592592
neural precursor cell expressed, developmentally down-regulated 1
IDBP-597268
neural precursor cell expressed, developmentally down-regulated 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:96907223-96953777
Strand Forward strand
Band q23.1
Transcripts
ENST00000266742 ENSP00000266742
ENST00000429527 ENSP00000404978
ENST00000411739 ENSP00000411307
ENST00000457368 ENSP00000407964
ENST00000554226 ENSP00000450881
ENST00000557478 ENSP00000451869
ENST00000557092 ENSP00000450757
ENST00000555806 ENSP00000450828
ENST00000555114
ENST00000557400
ENST00000553609 ENSP00000451830
ENST00000557454
ENST00000557644 ENSP00000451211
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 69 experimentally validated interaction(s) in this database.
Experimentally validated
Total 69 [view]
Protein-Protein 66 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 2 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0007067 mitotic nuclear division
Cellular Component
GO:0000242 pericentriolar material
GO:0000922 spindle pole
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005814 centriole
GO:0005829 cytosol
GO:0036064 ciliary basal body
GO:0045177 apical part of cell
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000019988
View Gene Order
ENSBTAG00000001894
Not yet available
Pathways
NETPATH
REACTOME
REACT_160315
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_15364
Loss of Nlp from mitotic centrosomes pathway
REACT_15451
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_15510
Recruitment of NuMA to mitotic centrosomes pathway
REACT_15296
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_115566
Cell Cycle pathway
REACT_15479
Centrosome maturation pathway
REACT_2203
G2/M Transition pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_21391
Mitotic G2-G2/M phases pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8NHV4
TrEMBL A0A024RBE5 G3V2M9 G3V4I9 G3V4L2
UniProt Splice Variant
Entrez Gene 121441
UniGene Hs.270084 Hs.743848
RefSeq NM_152905 XM_006719236 XM_006719237 NM_001135175 NM_001135176 NM_001135177 XM_005268644
HUGO HGNC:7723
OMIM 600372
CCDS CCDS9063 CCDS44955 CCDS44956
HPRD 02655
IMGT
EMBL AC007564 AC013417 AK093221 AK303656 AK315821 BC027605 CH471054
GenPept AAH27605 BAC04099 BAF98712 BAG64657 EAW97577 EAW97578 EAW97579 EAW97580
RNA Seq Atlas 121441

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca