Version 5.4
Mus musculus Gene: Sox21
Summary
InnateDB Gene IDBG-186289.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sox21
Gene Name SRY-box containing gene 21
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000061517
Encoded Proteins
IDBP-620578
SRY-box containing gene 21
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125285:
SRY-related HMG-box (SOX) genes encode a family of DNA-binding proteins containing a 79-amino acid HMG (high mobility group) domain that shares at least 50% sequence identity with the DNA-binding HMG box of the SRY protein (MIM 480000). SOX proteins are divided into 6 subgroups based on sequence similarity within and outside of the HMG domain. For additional background information on SOX genes, see SOX1 (MIM 602148).[supplied by OMIM, Apr 2004]
SRY-related HMG-box (SOX) genes encode a family of DNA-binding proteins containing a 79-amino acid HMG (high mobility group) domain that shares at least 50%% sequence identity with the DNA-binding HMG box of the SRY protein (MIM 480000). SOX proteins are divided into 6 subgroups based on sequence similarity within and outside of the HMG domain. For additional background information on SOX genes, see SOX1 (MIM 602148).[supplied by OMIM, Apr 2004]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:118233232-118237030
Strand Reverse strand
Band E4
Transcripts
ENSMUST00000170662 ENSMUSP00000127396
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
Biological Process
GO:0001942 hair follicle development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0042633 hair cycle
GO:0043588 skin development
GO:0048863 stem cell differentiation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000125285
View Gene Order
Cross-References
SwissProt Q811W0
TrEMBL
UniProt Splice Variant
Entrez Gene 223227
UniGene Mm.70950
RefSeq NM_177753
OMIM
CCDS CCDS27334
HPRD
IMGT
MGI ID MGI:2654070
MGI Symbol Sox21
EMBL AY069926 AY142959 BC069176 BC147556 BC147565
GenPept AAH69176 AAI47557 AAI47566 AAL49967 AAN60055
RNA Seq Atlas 223227

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca