InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Clasp1

Summary

InnateDB Gene

IDBG-186842.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Clasp1

Gene Name

CLIP associating protein 1

Synonyms

1700030C23Rik; 5730583A19Rik; B130045P17Rik; CLASP1alpha

Species

Mus musculus

Ensembl Gene

ENSMUSG00000064302

Encoded Proteins

IDBP-186846

CLIP associating protein 1

IDBP-186850

CLIP associating protein 1

IDBP-624257

CLIP associating protein 1

IDBP-715804

IDBP-788218

CLIP associating protein 1

IDBP-788220

CLIP associating protein 1

IDBP-788221

CLIP associating protein 1

IDBP-788222

CLIP associating protein 1

IDBP-788223

CLIP associating protein 1

IDBP-788224

CLIP associating protein 1

IDBP-788225

CLIP associating protein 1

IDBP-788226

CLIP associating protein 1

IDBP-788227

CLIP associating protein 1

IDBP-788228

CLIP associating protein 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000074054:
CLASPs, such as CLASP1, are nonmotor microtubule-associated proteins that interact with CLIPs (e.g., CLIP170; MIM 179838). CLASP1 is involved in the regulation of microtubule dynamics at the kinetochore and throughout the spindle (Maiato et al., 2003 [PubMed 12837247]).[supplied by OMIM, Mar 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:118389058-118612678

Strand

Forward strand

Band

E2.3

Transcripts

ENSMUST00000049404	ENSMUSP00000042266
ENSMUST00000070989	ENSMUSP00000067858
ENSMUST00000165223	ENSMUSP00000128089
ENSMUST00000178710	ENSMUSP00000137137
ENSMUST00000189676
ENSMUST00000190733	ENSMUSP00000140778
ENSMUST00000185405	ENSMUSP00000139619
ENSMUST00000189262	ENSMUSP00000140860
ENSMUST00000187713	ENSMUSP00000139526
ENSMUST00000189570	ENSMUSP00000140167
ENSMUST00000190135
ENSMUST00000191445	ENSMUSP00000140095
ENSMUST00000189738	ENSMUSP00000140665
ENSMUST00000186349	ENSMUSP00000141105
ENSMUST00000190571	ENSMUSP00000140019
ENSMUST00000188710	ENSMUSP00000140593
ENSMUST00000189216
ENSMUST00000189384
ENSMUST00000188441
ENSMUST00000187575

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0008017	microtubule binding
GO:0043515	kinetochore binding
GO:0051010	microtubule plus-end binding

Biological Process

GO:0000226	microtubule cytoskeleton organization
GO:0001578	microtubule bundle formation
GO:0007020	microtubule nucleation
GO:0007026	negative regulation of microtubule depolymerization
GO:0010458	exit from mitosis
GO:0031023	microtubule organizing center organization
GO:0031111	negative regulation of microtubule polymerization or depolymerization
GO:0034453	microtubule anchoring
GO:0051294	establishment of spindle orientation
GO:0051301	cell division

Cellular Component

GO:0000776	kinetochore
GO:0000777	condensed chromosome kinetochore
GO:0005794	Golgi apparatus
GO:0005813	centrosome
GO:0005828	kinetochore microtubule
GO:0005876	spindle microtubule
GO:0005881	cytoplasmic microtubule
GO:0005938	cell cortex
GO:0016020	membrane
GO:0030981	cortical microtubule cytoskeleton
GO:0031592	centrosomal corona
GO:0070062	extracellular vesicular exosome