InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CLASP1

Summary

InnateDB Gene

IDBG-642563.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CLASP1

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000019781

Encoded Proteins

IDBP-695070

cytoplasmic linker associated protein 1

IDBP-695079

cytoplasmic linker associated protein 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000074054:
CLASPs, such as CLASP1, are nonmotor microtubule-associated proteins that interact with CLIPs (e.g., CLIP170; MIM 179838). CLASP1 is involved in the regulation of microtubule dynamics at the kinetochore and throughout the spindle (Maiato et al., 2003 [PubMed 12837247]).[supplied by OMIM, Mar 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:73490617-73723487

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000065657	ENSBTAP00000056256
ENSBTAT00000031027	ENSBTAP00000030991

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0008017	microtubule binding
GO:0043515	kinetochore binding
GO:0051010	microtubule plus-end binding

Biological Process

GO:0000226	microtubule cytoskeleton organization
GO:0001578	microtubule bundle formation
GO:0007020	microtubule nucleation
GO:0007026	negative regulation of microtubule depolymerization
GO:0010458	exit from mitosis
GO:0031023	microtubule organizing center organization
GO:0031111	negative regulation of microtubule polymerization or depolymerization
GO:0034453	microtubule anchoring
GO:0051294	establishment of spindle orientation
GO:0051301	cell division

Cellular Component

GO:0000776	kinetochore
GO:0005794	Golgi apparatus
GO:0005813	centrosome
GO:0005828	kinetochore microtubule
GO:0005876	spindle microtubule
GO:0005881	cytoplasmic microtubule
GO:0005938	cell cortex
GO:0016020	membrane
GO:0030981	cortical microtubule cytoskeleton
GO:0031592	centrosomal corona
GO:0070062	extracellular vesicular exosome