Version 5.4
Mus musculus Gene: Ptk7
Summary
InnateDB Gene IDBG-187402.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ptk7
Gene Name PTK7 protein tyrosine kinase 7
Synonyms 8430404F20Rik; chz; mPTK7/CCK4
Species Mus musculus
Ensembl Gene ENSMUSG00000023972
Encoded Proteins
IDBP-187404
PTK7 protein tyrosine kinase 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112655:
This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:46564451-46629504
Strand Reverse strand
Band C
Transcripts
ENSMUST00000044442 ENSMUSP00000043703
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0001736 establishment of planar polarity
GO:0001843 neural tube closure
GO:0003401 axis elongation
GO:0006468 protein phosphorylation
GO:0007155 cell adhesion
GO:0010976 positive regulation of neuron projection development
GO:0016477 cell migration
GO:0031532 actin cytoskeleton reorganization
GO:0042060 wound healing
GO:0045198 establishment of epithelial cell apical/basal polarity
GO:0060026 convergent extension
GO:0060070 canonical Wnt signaling pathway
GO:0060484 lung-associated mesenchyme development
GO:0071300 cellular response to retinoic acid
GO:0090103 cochlea morphogenesis
GO:0090179 planar cell polarity pathway involved in neural tube closure
Cellular Component
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000112655
View Gene Order
ENSBTAG00000012761
Not yet available
Cross-References
SwissProt Q8BKG3
TrEMBL Q3V2W2
UniProt Splice Variant
Entrez Gene 71461
UniGene Mm.181833
RefSeq NM_175168 XM_006524922 XM_006524923 XM_006524924
OMIM
CCDS CCDS37637
HPRD
IMGT
MGI ID MGI:1918711
MGI Symbol Ptk7
EMBL AB055408 AF531873 AK018379 AK053044 AK087891 AK163135 AY303976 BC027800 BC076578
GenPept AAH27800 AAH76578 AAQ10071 AAQ73496 BAC35248 BAC53806 BAE37208 BAE43251 BAE43393
RNA Seq Atlas 71461

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca