InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Taf13

Summary

InnateDB Gene

IDBG-187669.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Taf13

Gene Name

TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor

Synonyms

1810004N01Rik; 2010309N11Rik; AI847295; TAFII18

Species

Mus musculus

Ensembl Gene

ENSMUSG00000048100

Encoded Proteins

IDBP-536315

TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197780:
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:108571698-108583222

Strand

Forward strand

Band

Transcripts

ENSMUST00000056292
ENSMUST00000131814
ENSMUST00000143054	ENSMUSP00000121346
ENSMUST00000139603

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0046982	protein heterodimerization activity