Version 5.4
Bos taurus Gene: TAF13
Summary
InnateDB Gene IDBG-635615.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAF13
Gene Name Transcription initiation factor TFIID subunit 13
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000031656
Encoded Proteins
IDBP-687459
Transcription initiation factor TFIID subunit 13
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197780:
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:34418712-34426687
Strand Forward strand
Band
Transcripts
ENSBTAT00000044882 ENSBTAP00000042334
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005669 transcription factor TFIID complex
GO:0005730 nucleolus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000197780
View Gene Order
ENSMUSG00000048100
View Gene Order
Pathways
NETPATH
REACTOME
REACT_209718
RNA Polymerase II Transcription pathway
REACT_205499
RNA Polymerase II Pre-transcription Events pathway
REACT_202835
RNA Polymerase II Promoter Escape pathway
REACT_226022
Gene Expression pathway
REACT_207660
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
REACT_208384
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
REACT_207656
RNA Polymerase II Transcription Initiation pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1655
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
REACT_22107
RNA Polymerase II Pre-transcription Events pathway
REACT_2089
RNA Polymerase II Promoter Escape pathway
REACT_1851
RNA Polymerase II Transcription Initiation pathway
REACT_834
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
REACT_6332
HIV Transcription Initiation pathway
REACT_6253
RNA Polymerase II HIV Promoter Escape pathway
REACT_6233
Transcription of the HIV genome pathway
REACT_6361
Late Phase of HIV Life Cycle pathway
REACT_1366
RNA Polymerase II Transcription pathway
REACT_6256
HIV Life Cycle pathway
REACT_6185
HIV Infection pathway
REACT_71
Gene Expression pathway
REACT_116125
Disease pathway
REACT_230204
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
REACT_244380
RNA Polymerase II Transcription Initiation pathway
REACT_255334
RNA Polymerase II Promoter Escape pathway
REACT_232708
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
REACT_255009
RNA Polymerase II Pre-transcription Events pathway
REACT_233572
Gene Expression pathway
REACT_242255
RNA Polymerase II Transcription pathway
KEGG
hsa03022
Basal transcription factors pathway
mmu03022
Basal transcription factors pathway
INOH
PID NCI
Cross-References
SwissProt Q148M7
TrEMBL
UniProt Splice Variant
Entrez Gene 790401
UniGene Bt.26935
RefSeq NM_001075597 XM_001256882
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC118136
GenPept AAI18137
RNA Seq Atlas 513065 790401

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca