Version 5.4
Mus musculus Gene: Zfp384
Summary
InnateDB Gene IDBG-188708.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zfp384
Gene Name zinc finger protein 384
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038346
Encoded Proteins
IDBP-131381
zinc finger protein 384
IDBP-188712
zinc finger protein 384
IDBP-188714
zinc finger protein 384
IDBP-188716
zinc finger protein 384
IDBP-256053
zinc finger protein 384
IDBP-256055
zinc finger protein 384
IDBP-256057
zinc finger protein 384
IDBP-256059
zinc finger protein 384
IDBP-538942
zinc finger protein 384
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000126746:
This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:125009145-125037870
Strand Forward strand
Band F2
Transcripts
ENSMUST00000054553 ENSMUSP00000086354
ENSMUST00000088308 ENSMUSP00000085648
ENSMUST00000084275 ENSMUSP00000081296
ENSMUST00000046064 ENSMUSP00000037986
ENSMUST00000112428 ENSMUSP00000108047
ENSMUST00000112427 ENSMUSP00000108046
ENSMUST00000112425 ENSMUSP00000108044
ENSMUST00000112424 ENSMUSP00000108043
ENSMUST00000132863
ENSMUST00000145138
ENSMUST00000144308
ENSMUST00000131555
ENSMUST00000152752 ENSMUSP00000117330
ENSMUST00000140835
ENSMUST00000145566
ENSMUST00000137325
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0017124 SH3 domain binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006913 nucleocytoplasmic transport
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0050714 positive regulation of protein secretion
Cellular Component
GO:0005634 nucleus
GO:0005925 focal adhesion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000126746
View Gene Order
ENSBTAG00000017072
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.108677 Mm.410212 Mm.415768 Mm.490118
RefSeq NM_001252083 NM_175557 XM_006506203 XM_006506204
OMIM
CCDS CCDS39631 CCDS57448
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca