Bos taurus Gene: BT.45809
Summary
InnateDB Gene IDBG-640310.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.45809
Gene Name zinc finger protein 384
Synonyms NMP4; NP
Species Bos taurus
Ensembl Gene ENSBTAG00000017072
Encoded Proteins
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000126746:
This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:104123599-104143236
Strand Forward strand
Band
Transcripts
ENSBTAT00000022702 ENSBTAP00000022702
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding
Biological Process
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL A9X431 F1MGZ7
UniProt Splice Variant
Entrez Gene 515007
UniGene Bt.45809
RefSeq NM_001192394 XM_005207145
HUGO HGNC:11955
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02014462 DQ323645
GenPept ABD27876
RNA Seq Atlas 515007