Mus musculus Gene: Smug1
Summary
InnateDB Gene IDBG-189457.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Smug1
Gene Name single-strand selective monofunctional uracil DNA glycosylase
Synonyms 1200013B09Rik; A930006H09Rik; C85220
Species Mus musculus
Ensembl Gene ENSMUSG00000036061
Encoded Proteins
single-strand selective monofunctional uracil DNA glycosylase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123415:
This gene encodes a protein that participates in base excision repair by removing uracil from single- and double-stranded DNA. Many alternatively spliced transcript variants exist for this gene; the full-length nature is known for some but not all of the variants. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:103153307-103158002
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000064067 ENSMUSP00000065835
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000702 oxidized base lesion DNA N-glycosylase activity
GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
GO:0003697 single-stranded DNA binding
GO:0004844 uracil DNA N-glycosylase activity
GO:0005515 protein binding
GO:0017065 single-strand selective uracil DNA N-glycosylase activity
GO:0019104 DNA N-glycosylase activity
Biological Process
GO:0000737 DNA catabolic process, endonucleolytic
GO:0006281 DNA repair
GO:0006284 base-excision repair
Cellular Component
GO:0005730 nucleolus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Base-free sugar-phosphate removal via the single-nucleotide replacement pathway pathway
Displacement of DNA glycosylase by APE1 pathway
Resolution of AP sites via the single-nucleotide replacement pathway pathway
Base Excision Repair pathway
Base-Excision Repair, AP Site Formation pathway
Resolution of AP sites via the multiple-nucleotide patch replacement pathway pathway
Depyrimidination pathway
DNA Repair pathway
Cleavage of the damaged pyrimidine pathway
Removal of DNA patch containing abasic residue pathway
Recognition and association of DNA glycosylase with site containing an affected pyrimidine pathway
Resolution of Abasic Sites (AP sites) pathway
KEGG
Base excision repair pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Displacement of DNA glycosylase by APE1 pathway
Base-free sugar-phosphate removal via the single-nucleotide replacement pathway pathway
Resolution of AP sites via the single-nucleotide replacement pathway pathway
Cleavage of the damaged pyrimidine pathway
Removal of DNA patch containing abasic residue pathway
Resolution of AP sites via the multiple-nucleotide patch replacement pathway pathway
Recognition and association of DNA glycosylase with site containing an affected pyrimidine pathway
Resolution of Abasic Sites (AP sites) pathway
Depyrimidination pathway
Base Excision Repair pathway
Base-Excision Repair, AP Site Formation pathway
DNA Repair pathway
Cleavage of the damaged pyrimidine pathway
Base-Excision Repair, AP Site Formation pathway
Resolution of Abasic Sites (AP sites) pathway
Displacement of DNA glycosylase by APE1 pathway
DNA Repair pathway
Recognition and association of DNA glycosylase with site containing an affected pyrimidine pathway
Removal of DNA patch containing abasic residue pathway
Base Excision Repair pathway
Resolution of AP sites via the single-nucleotide replacement pathway pathway
Base-free sugar-phosphate removal via the single-nucleotide replacement pathway pathway
Depyrimidination pathway
Resolution of AP sites via the multiple-nucleotide patch replacement pathway pathway
KEGG
Base excision repair pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_027885 XM_006521413 XM_006521414 XM_006521415
OMIM
CCDS CCDS27898
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas