Mus musculus Gene: Treml1
Summary
InnateDB Gene IDBG-189902.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Treml1
Gene Name triggering receptor expressed on myeloid cells-like 1
Synonyms 5430401J17Rik; TLT-1
Species Mus musculus
Ensembl Gene ENSMUSG00000023993
Encoded Proteins
triggering receptor expressed on myeloid cells-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000161911:
This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:48359916-48367174
Strand Forward strand
Band C
Transcripts
ENSMUST00000024792 ENSMUSP00000024792
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0009968 negative regulation of signal transduction
GO:0019722 calcium-mediated signaling
GO:0030168 platelet activation
GO:0042060 wound healing
Cellular Component
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0031091 platelet alpha granule
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q8K558
TrEMBL
UniProt Splice Variant
Entrez Gene 71326
UniGene Mm.90177
RefSeq NM_001289457 NM_027763 XM_006524921
OMIM
CCDS CCDS28866
HPRD
IMGT
MGI ID MGI:1918576
MGI Symbol Treml1
EMBL AK017256 AY078502 AY286071 BC138399
GenPept AAI38400 AAL85488 AAP33393 BAB30655
RNA Seq Atlas 71326