Mus musculus Gene: Cd9
Summary
InnateDB Gene IDBG-189938.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cd9
Gene Name CD9 antigen
Synonyms Tspan29
Species Mus musculus
Ensembl Gene ENSMUSG00000030342
Encoded Proteins
CD9 antigen
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000010278:
This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:125460266-125494791
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000032492 ENSMUSP00000032492
ENSMUST00000130132
ENSMUST00000140024
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 27 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005178 integrin binding
GO:0005515 protein binding
Biological Process
GO:0006928 cellular component movement
GO:0007155 cell adhesion
GO:0007342 fusion of sperm to egg plasma membrane
GO:0007420 brain development
GO:0008285 negative regulation of cell proliferation
GO:0009414 response to water deprivation
GO:0014003 oligodendrocyte development
GO:0030913 paranodal junction assembly
Cellular Component
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Platelet degranulation pathway
Hemostasis pathway
Platelet activation, signaling and aggregation pathway
Sperm:Oocyte Membrane Binding pathway
Fertilization pathway
Reproduction pathway
Response to elevated platelet cytosolic Ca2+ pathway
KEGG
Hematopoietic cell lineage pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Platelet degranulation pathway
Response to elevated platelet cytosolic Ca2+ pathway
Platelet activation, signaling and aggregation pathway
Fertilization pathway
Reproduction pathway
Sperm:Oocyte Membrane Binding pathway
Hemostasis pathway
Platelet degranulation pathway
Fertilization pathway
Hemostasis pathway
Platelet activation, signaling and aggregation pathway
Response to elevated platelet cytosolic Ca2+ pathway
Reproduction pathway
Sperm:Oocyte Membrane Binding pathway
KEGG
Hematopoietic cell lineage pathway
INOH
PID NCI
a6b1 and a6b4 Integrin signaling
Cross-References
SwissProt P40240
TrEMBL
UniProt Splice Variant
Entrez Gene 12527
UniGene Mm.210676 Mm.470273
RefSeq NM_007657
OMIM
CCDS CCDS20551
HPRD
IMGT
MGI ID MGI:88348
MGI Symbol Cd9
EMBL AK002251 AK012793 AK151443 AK151619 AK170310 BC070474 L08115
GenPept AAA37405 AAH70474 BAB21965 BAB28473 BAE30405 BAE30556 BAE41707
RNA Seq Atlas 12527