Version 5.4
Mus musculus Gene: Ano2
Summary
InnateDB Gene IDBG-190085.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ano2
Gene Name anoctamin 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038115
Encoded Proteins
IDBP-531816
anoctamin 2
IDBP-538020
anoctamin 2
IDBP-533140
anoctamin 2
IDBP-540168
anoctamin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000047617:
ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009 [PubMed 19015192]).[supplied by OMIM, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:125690419-126040126
Strand Forward strand
Band F3
Transcripts
ENSMUST00000160496 ENSMUSP00000125303
ENSMUST00000159111
ENSMUST00000161619 ENSMUSP00000125426
ENSMUST00000161293 ENSMUSP00000124001
ENSMUST00000160317
ENSMUST00000159984 ENSMUSP00000123965
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005229 intracellular calcium activated chloride channel activity
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006821 chloride transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0031513 nonmotile primary cilium
GO:0034707 chloride channel complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000047617
View Gene Order
ENSBTAG00000012246
Not yet available
Pathways
NETPATH
REACTOME
REACT_196640
Stimuli-sensing channels pathway
REACT_268398
Orphan transporters pathway
REACT_262350
Ion channel transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160189
Stimuli-sensing channels pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_267716
Orphan transporters pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8CFW1
TrEMBL E0CYP6 M1H0B0
UniProt Splice Variant
Entrez Gene 243634
UniGene Mm.333398
RefSeq NM_153589 XM_006506115 XM_006506116 XM_006506117 XM_006506118 XM_006506119
OMIM
CCDS CCDS39643
HPRD
IMGT
MGI ID MGI:2387214
MGI Symbol Ano2
EMBL AC122284 AC153372 AC153578 AC153868 AC155837 AK044763 BC033409 FJ384096 KC164759
GenPept AAH33409 ACL36051 AGE31681 BAC32073
RNA Seq Atlas 243634

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca