InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Kdm6b

Summary

InnateDB Gene

IDBG-190700.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Kdm6b

Gene Name

KDM1 lysine (K)-specific demethylase 6B

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000018476

Encoded Proteins

IDBP-190702

KDM1 lysine (K)-specific demethylase 6B

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132510:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:69398508-69413675

Strand

Reverse strand

Band

Transcripts

ENSMUST00000094077	ENSMUSP00000091620
ENSMUST00000156562

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	6 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008013	beta-catenin binding
GO:0043565	sequence-specific DNA binding
GO:0046872	metal ion binding
GO:0051213	dioxygenase activity
GO:0071558	histone demethylase activity (H3-K27 specific)

Biological Process

GO:0006954	inflammatory response
GO:0016577	histone demethylation
GO:0045446	endothelial cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048333	mesodermal cell differentiation
GO:0055007	cardiac muscle cell differentiation
GO:0055114	oxidation-reduction process
GO:0070301	cellular response to hydrogen peroxide
GO:0071557	histone H3-K27 demethylation