Version 5.4
Bos taurus Gene: KDM6B
Summary
InnateDB Gene IDBG-635240.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KDM6B
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000048062
Encoded Proteins
IDBP-687110
lysine (K)-specific demethylase 6B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132510:
Gene Information
Type Protein coding
Genomic Location Chromosome 19:28147259-28155406
Strand Forward strand
Band
Transcripts
ENSBTAT00000063022 ENSBTAP00000056319
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0043565 sequence-specific DNA binding
GO:0071558 histone demethylase activity (H3-K27 specific)
Biological Process
GO:0016577 histone demethylation
GO:0045446 endothelial cell differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048333 mesodermal cell differentiation
GO:0055007 cardiac muscle cell differentiation
GO:0070301 cellular response to hydrogen peroxide
GO:0071557 histone H3-K27 demethylation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000132510
View Gene Order
ENSMUSG00000018476
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_120956
Cellular responses to stress pathway
REACT_228178
HDMs demethylate histones pathway
REACT_169274
Cellular Senescence pathway
REACT_172623
Chromatin organization pathway
REACT_172633
Chromatin modifying enzymes pathway
REACT_169436
Oxidative Stress Induced Senescence pathway
REACT_188970
Oxidative Stress Induced Senescence pathway
REACT_218274
Chromatin organization pathway
REACT_256030
HDMs demethylate histones pathway
REACT_188957
Cellular responses to stress pathway
REACT_202766
Chromatin modifying enzymes pathway
REACT_188820
Cellular Senescence pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL G3N346
UniProt Splice Variant
Entrez Gene 100140276
UniGene Bt.92039
RefSeq XM_003583567 XM_003587412
HUGO HGNC:29012
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02048802
GenPept
RNA Seq Atlas 100140276
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca