InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Slc26a9

Summary

InnateDB Gene

IDBG-191410.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc26a9

Gene Name

solute carrier family 26, member 9

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000042268

Encoded Proteins

IDBP-191412

solute carrier family 26, member 9

IDBP-537783

solute carrier family 26, member 9

IDBP-788896

solute carrier family 26, member 9

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174502:
This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns. The product of this gene is a highly selective chloride ion channel regulated by WNK kinases. Alternative splicing results in multiple transcript variants encoding differing isoforms.[provided by RefSeq, Dec 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:131744022-131771504

Strand

Forward strand

Band

Transcripts

ENSMUST00000049027	ENSMUSP00000036916
ENSMUST00000130544
ENSMUST00000147800	ENSMUSP00000122075
ENSMUST00000186122	ENSMUSP00000141171

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005254	chloride channel activity
GO:0008271	secondary active sulfate transmembrane transporter activity
GO:0015106	bicarbonate transmembrane transporter activity
GO:0015116	sulfate transmembrane transporter activity
GO:0015301	anion:anion antiporter activity
GO:0051117	ATPase binding

Biological Process

GO:0006820	anion transport
GO:0006821	chloride transport
GO:0006885	regulation of pH
GO:0008272	sulfate transport
GO:0010628	positive regulation of gene expression
GO:0015701	bicarbonate transport
GO:0055085	transmembrane transport
GO:1902358	sulfate transmembrane transport
GO:1902476	chloride transmembrane transport

Cellular Component

GO:0009986	cell surface
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0070062	extracellular vesicular exosome

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000174502

View Gene Order

ENSBTAG00000001382

Not yet available

Pathways

NETPATH

REACTOME

REACT_258881

Multifunctional anion exchangers pathway

REACT_247550

SLC-mediated transmembrane transport pathway

REACT_251788

Transport of inorganic cations/anions and amino acids/oligopeptides pathway

REACT_253400

Transmembrane transport of small molecules pathway

KEGG

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_19357

Multifunctional anion exchangers pathway

REACT_19397

Transport of inorganic cations/anions and amino acids/oligopeptides pathway

REACT_15518

Transmembrane transport of small molecules pathway

REACT_19118

SLC-mediated transmembrane transport pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

Q8BU91

TrEMBL

D3Z1A3

UniProt Splice Variant

Entrez Gene

320718

UniGene

Mm.482704

RefSeq

NM_177243 XM_006529700 XM_006529701

OMIM

CCDS

CCDS15273

HPRD

IMGT

MGI ID

MGI:2444594

MGI Symbol

Slc26a9

EMBL

AC138277 AK078966 AK086815 AY034145

GenPept

AAK54448 BAC37482 BAC39749

RNA Seq Atlas

320718