Mus musculus Gene: Ptp4a2 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-191662.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Ptp4a2 | ||||||||||||||||||||||
Gene Name | protein tyrosine phosphatase 4a2 | ||||||||||||||||||||||
Synonyms | Prl-2 | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000028788 | ||||||||||||||||||||||
Encoded Proteins |
protein tyrosine phosphatase 4a2
protein tyrosine phosphatase 4a2
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Protein Structure |
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Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184007:
The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. [provided by RefSeq, Aug 2010] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 4:129811219-129850003 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | D2.2 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME | |||||||||||||||||||||||
KEGG | |||||||||||||||||||||||
INOH | |||||||||||||||||||||||
PID NCI |
Signaling events mediated by PRL
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Cross-References | |||||||||||||||||||||||
SwissProt | O70274 | ||||||||||||||||||||||
TrEMBL | Q3UXF9 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 19244 | ||||||||||||||||||||||
UniGene | Mm.193688 Mm.394150 Mm.403155 Mm.406457 Mm.439824 Mm.446241 Mm.470778 | ||||||||||||||||||||||
RefSeq | NM_008974 NM_001164745 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS18704 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:1277117 | ||||||||||||||||||||||
MGI Symbol | Ptp4a2 | ||||||||||||||||||||||
EMBL | AF035644 AK033092 AK045093 AK135662 AK155895 BC086794 BC087551 | ||||||||||||||||||||||
GenPept | AAC15874 AAH86794 AAH87551 BAC28149 BAC32217 BAE22604 BAE33489 | ||||||||||||||||||||||
RNA Seq Atlas | 19244 | ||||||||||||||||||||||