Version 5.4
Mus musculus Gene: Zbtb38
Summary
InnateDB Gene IDBG-192133.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zbtb38
Gene Name zinc finger and BTB domain containing 38
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000040433
Encoded Proteins
IDBP-192135
zinc finger and BTB domain containing 38
IDBP-540198
zinc finger and BTB domain containing 38
IDBP-535049
zinc finger and BTB domain containing 38
IDBP-541367
zinc finger and BTB domain containing 38
IDBP-536242
zinc finger and BTB domain containing 38
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000177311:
The protein encoded by this gene is a zinc finger transcriptional activator that binds methylated DNA. The encoded protein can form homodimers or heterodimers through the zinc finger domains. In mouse, inhibition of this protein has been associated with apoptosis in some cell types. [provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:96682770-96752831
Strand Reverse strand
Band E3.3
Transcripts
ENSMUST00000093798 ENSMUSP00000091315
ENSMUST00000152594 ENSMUSP00000121753
ENSMUST00000126066 ENSMUSP00000114300
ENSMUST00000140121 ENSMUSP00000120040
ENSMUST00000128269 ENSMUSP00000121871
ENSMUST00000143906
ENSMUST00000147314
ENSMUST00000130078
ENSMUST00000137858
ENSMUST00000124186
ENSMUST00000132060
ENSMUST00000143403
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008327 methyl-CpG binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0072562 blood microparticle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000177311
View Gene Order
ENSBTAG00000040061
Not yet available
Cross-References
SwissProt
TrEMBL D3Z1Y7 Q8BW24
UniProt Splice Variant
Entrez Gene 245007
UniGene Mm.259909 Mm.390207 Mm.398702 Mm.468782 Mm.485954
RefSeq NM_175537
OMIM
CCDS CCDS40731
HPRD
IMGT
MGI ID MGI:2442866
MGI Symbol Zbtb38
EMBL AC121951 AK054529
GenPept BAC35812
RNA Seq Atlas 245007

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca