Version 5.4
Homo sapiens Gene: ZBTB38
Summary
InnateDB Gene IDBG-59081.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZBTB38
Gene Name zinc finger and BTB domain containing 38
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000177311
Encoded Proteins
IDBP-59083
zinc finger and BTB domain containing 38
IDBP-384559
zinc finger and BTB domain containing 38
IDBP-477991
zinc finger and BTB domain containing 38
IDBP-476085
zinc finger and BTB domain containing 38
IDBP-475925
zinc finger and BTB domain containing 38
IDBP-476736
zinc finger and BTB domain containing 38
IDBP-477234
zinc finger and BTB domain containing 38
IDBP-481195
zinc finger and BTB domain containing 38
IDBP-481499
zinc finger and BTB domain containing 38
IDBP-478998
zinc finger and BTB domain containing 38
IDBP-474494
zinc finger and BTB domain containing 38
IDBP-484885
zinc finger and BTB domain containing 38
IDBP-482764
zinc finger and BTB domain containing 38
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a zinc finger transcriptional activator that binds methylated DNA. The encoded protein can form homodimers or heterodimers through the zinc finger domains. In mouse, inhibition of this protein has been associated with apoptosis in some cell types. [provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:141324213-141449792
Strand Forward strand
Band q23
Transcripts
ENST00000321464 ENSP00000372635
ENST00000441582 ENSP00000406955
ENST00000509842 ENSP00000426931
ENST00000513619
ENST00000512276
ENST00000507657
ENST00000507722 ENSP00000421037
ENST00000512327
ENST00000513249
ENST00000503809 ENSP00000422051
ENST00000513258 ENSP00000426288
ENST00000506623
ENST00000509883 ENSP00000424254
ENST00000514251 ENSP00000426387
ENST00000510338 ENSP00000425705
ENST00000504673 ENSP00000422347
ENST00000513570 ENSP00000422757
ENST00000510726 ENSP00000422081
ENST00000509813 ENSP00000422894
ENST00000512769
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008327 methyl-CpG binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0072562 blood microparticle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040433
View Gene Order
ENSBTAG00000040061
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.618484 Hs.626213 Hs.666580 Hs.743268
RefSeq NM_001080412 XM_005247255 XM_005247256 XM_005247257 XM_005247258 XM_005247261 XM_005247262 XM_005247263 XM_006713559
HUGO
OMIM
CCDS CCDS43157
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca