Version 5.4
Mus musculus Gene: Synm
Summary
InnateDB Gene IDBG-192311.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Synm
Gene Name synemin, intermediate filament protein
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000030554
Encoded Proteins
IDBP-192313
synemin, intermediate filament protein
IDBP-192315
synemin, intermediate filament protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182253:
The protein encoded by this gene is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and provides an important structural support in muscle. Two alternatively spliced variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:67730161-67759742
Strand Reverse strand
Band C
Transcripts
ENSMUST00000051389 ENSMUSP00000050987
ENSMUST00000074233 ENSMUSP00000073855
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0008307 structural constituent of muscle
GO:0017166 vinculin binding
GO:0019215 intermediate filament binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005882 intermediate filament
GO:0005912 adherens junction
GO:0016020 membrane
GO:0043034 costamere
GO:0060053 neurofilament cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000182253
View Gene Order
ENSBTAG00000011752
Not yet available
Cross-References
SwissProt Q70IV5
TrEMBL Q3TSN2 Q80XS8
UniProt Splice Variant
Entrez Gene 233335
UniGene Mm.60526
RefSeq NM_183312 NM_201639 NM_207663
OMIM
CCDS CCDS39982 CCDS39983
HPRD
IMGT
MGI ID MGI:2661187
MGI Symbol Synm
EMBL AC158296 AJ579700 AJ579701 AJ579702 AK143019 AK161935 AK172937 BC042785
GenPept AAH42785 BAD32215 BAE25250 BAE36643 CAE30277 CAE30278 CAE30279
RNA Seq Atlas 233335

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca