Version 5.4
Mus musculus Gene: Foxn4
Summary
InnateDB Gene IDBG-192324.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Foxn4
Gene Name forkhead box N4
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000042002
Encoded Proteins
IDBP-192326
forkhead box N4
IDBP-622106
forkhead box N4
IDBP-622108
forkhead box N4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139445:
Members of the winged-helix/forkhead family of transcription factors, such as FOXN4, are characterized by a 110-amino acid DNA-binding domain that can fold into a variant of the helix-turn-helix motif consisting of 3 alpha helices flanked by 2 large loops or wings. These transcription factors are involved in a variety of biologic processes as key regulators in development and metabolism (Li et al., 2004 [PubMed 15363391]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:114254164-114273807
Strand Reverse strand
Band F
Transcripts
ENSMUST00000044790 ENSMUSP00000047951
ENSMUST00000129530 ENSMUSP00000126256
ENSMUST00000144050 ENSMUSP00000126361
ENSMUST00000147953
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001158 enhancer sequence-specific DNA binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0008134 transcription factor binding
GO:0008301 DNA binding, bending
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001947 heart looping
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0007389 pattern specification process
GO:0008016 regulation of heart contraction
GO:0009888 tissue development
GO:0010842 retina layer formation
GO:0030154 cell differentiation
GO:0035881 amacrine cell differentiation
GO:0036302 atrioventricular canal development
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048513 organ development
GO:0048663 neuron fate commitment
GO:0051090 regulation of sequence-specific DNA binding transcription factor activity
GO:0060579 ventral spinal cord interneuron fate commitment
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000139445
View Gene Order
ENSBTAG00000010847
Not yet available
Cross-References
SwissProt
TrEMBL F6ZBN9
UniProt Splice Variant
Entrez Gene 116810
UniGene Mm.17709
RefSeq NM_148935 XM_006530121 XM_006530122 XM_006530123
OMIM
CCDS CCDS19562
HPRD
IMGT
MGI ID MGI:2151057
MGI Symbol Foxn4
EMBL AC122282
GenPept
RNA Seq Atlas 116810

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca