Version 5.4
Mus musculus Gene: Msrb3
Summary
InnateDB Gene IDBG-192680.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Msrb3
Gene Name methionine sulfoxide reductase B3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000051236
Encoded Proteins
IDBP-192682
methionine sulfoxide reductase B3
IDBP-536152
methionine sulfoxide reductase B3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174099:
The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula. [provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:120781096-120899101
Strand Reverse strand
Band D2
Transcripts
ENSMUST00000092143 ENSMUSP00000089781
ENSMUST00000139961
ENSMUST00000130950 ENSMUSP00000115269
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0033743 peptide-methionine (R)-S-oxide reductase activity
Biological Process
GO:0006979 response to oxidative stress
GO:0030091 protein repair
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000174099
View Gene Order
ENSBTAG00000044017
Not yet available
Cross-References
SwissProt
TrEMBL D3YUC9
UniProt Splice Variant
Entrez Gene 320183
UniGene Mm.169755 Mm.398652
RefSeq NM_177092 XM_006513764 XM_006513765
OMIM
CCDS CCDS24208
HPRD
IMGT
MGI ID MGI:2443538
MGI Symbol Msrb3
EMBL AC138388
GenPept
RNA Seq Atlas 320183

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca