Version 5.4
Mus musculus Gene: Clpp
Summary
InnateDB Gene IDBG-193203.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Clpp
Gene Name ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit
Synonyms AU019820; D17Wsu160e
Species Mus musculus
Ensembl Gene ENSMUSG00000002660
Encoded Proteins
IDBP-193205
caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125656:
The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:56990264-56996371
Strand Forward strand
Band D
Transcripts
ENSMUST00000002735 ENSMUSP00000002735
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004252 serine-type endopeptidase activity
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0006515 misfolded or incompletely synthesized protein catabolic process
GO:0051260 protein homooligomerization
GO:0051603 proteolysis involved in cellular protein catabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0009368 endopeptidase Clp complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000125656
View Gene Order
ENSBTAG00000014712
Not yet available
Cross-References
SwissProt O88696
TrEMBL Q3UGW4 Q8CF81
UniProt Splice Variant
Entrez Gene 53895
UniGene Mm.287892 Mm.406143
RefSeq NM_017393
OMIM
CCDS CCDS28920
HPRD
IMGT
MGI ID MGI:1858213
MGI Symbol Clpp
EMBL AJ005253 AJ012249 AJ012250 AJ012251 AJ012252 AJ012253 AK002238 AK004024 AK145765 AK147719 AK168053 BC001998
GenPept AAH01998 BAB23132 BAC24984 BAE26636 BAE28093 BAE40033 CAA06443 CAA09966
RNA Seq Atlas 53895

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca