Version 5.4
Mus musculus Gene: Ticrr
Summary
InnateDB Gene IDBG-194114.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ticrr
Gene Name TOPBP1-interacting checkpoint and replication regulator
Synonyms 5730590G19Rik; BC028450; Lrrk1
Species Mus musculus
Ensembl Gene ENSMUSG00000046591
Encoded Proteins
IDBP-194116
RIKEN cDNA 5730590G19 gene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140534:
Treslin is involved in the initiation of DNA replication (Kumagai et al., 2010 [PubMed 20116089]).[supplied by OMIM, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:79660196-79698134
Strand Forward strand
Band D2
Transcripts
ENSMUST00000035977 ENSMUSP00000041377
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0005515 protein binding
Biological Process
GO:0000075 cell cycle checkpoint
GO:0001731 formation of translation preinitiation complex
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0010212 response to ionizing radiation
GO:0030174 regulation of DNA-dependent DNA replication initiation
GO:0033314 mitotic DNA replication checkpoint
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000140534
View Gene Order
ENSBTAG00000002418
Not yet available
Cross-References
SwissProt Q8BQ33
TrEMBL Q3UV49
UniProt Splice Variant
Entrez Gene 77011
UniGene Mm.28132
RefSeq NM_029835
OMIM
CCDS CCDS21384
HPRD
IMGT
MGI ID MGI:1924261
MGI Symbol Ticrr
EMBL AC114988 AC158582 AK033104 AK041726 AK051639 AK137597 BC058634 BC158103
GenPept AAH58634 AAI58104 BAC28152 BAC31045 BAC34701 BAE23424
RNA Seq Atlas 77011

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca