Version 5.4
Homo sapiens Gene: TICRR
Summary
InnateDB Gene IDBG-29397.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TICRR
Gene Name TOPBP1-interacting checkpoint and replication regulator
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000140534
Encoded Proteins
IDBP-29399
chromosome 15 open reading frame 42
IDBP-592986
chromosome 15 open reading frame 42
IDBP-584904
chromosome 15 open reading frame 42
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Treslin is involved in the initiation of DNA replication (Kumagai et al., 2010 [PubMed 20116089]).[supplied by OMIM, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:89575482-89631056
Strand Forward strand
Band q26.1
Transcripts
ENST00000268138 ENSP00000268138
ENST00000560985 ENSP00000453306
ENST00000561095 ENSP00000453922
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0005515 protein binding
Biological Process
GO:0000075 cell cycle checkpoint
GO:0001731 formation of translation preinitiation complex
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0010212 response to ionizing radiation
GO:0030174 regulation of DNA-dependent DNA replication initiation
GO:0033314 mitotic DNA replication checkpoint
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000046591
View Gene Order
ENSBTAG00000002418
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 90381
UniGene Hs.441708
RefSeq NM_152259
HUGO HGNC:28704
OMIM 613298
CCDS CCDS10352
HPRD 11357
IMGT
EMBL
GenPept
RNA Seq Atlas 90381

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca