Version 5.4
Mus musculus Gene: Syt2
Summary
InnateDB Gene IDBG-194117.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Syt2
Gene Name synaptotagmin II
Synonyms mKIAA4194; R74640
Species Mus musculus
Ensembl Gene ENSMUSG00000026452
Encoded Proteins
IDBP-400478
synaptotagmin II
IDBP-789788
synaptotagmin II
IDBP-789789
synaptotagmin II
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143858:
Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:134646677-134762593
Strand Forward strand
Band E4
Transcripts
ENSMUST00000121990 ENSMUSP00000112438
ENSMUST00000187725 ENSMUSP00000141156
ENSMUST00000188842 ENSMUSP00000140081
ENSMUST00000187702
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005544 calcium-dependent phospholipid binding
Biological Process
GO:0006810 transport
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
GO:0042584 chromaffin granule membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143858
View Gene Order
ENSBTAG00000047648
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11184
Neurotoxicity of clostridium toxins pathway
REACT_200782
Toxicity of botulinum toxin type B (BoNT/B) pathway
REACT_228211
Uptake and actions of bacterial toxins pathway
REACT_116125
Disease pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q9JM87
UniProt Splice Variant
Entrez Gene 20980
UniGene
RefSeq NM_009307 XM_006529322 XM_006529323 XM_006529324
OMIM
CCDS CCDS15312
HPRD
IMGT
MGI ID MGI:99666
MGI Symbol Syt2
EMBL AB036514
GenPept BAA95588
RNA Seq Atlas 20980

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca