Mus musculus Gene: Gpr3
Summary
InnateDB Gene IDBG-194760.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpr3
Gene Name G-protein coupled receptor 3
Synonyms Gpcr20; Gpcr21; Gpcr3
Species Mus musculus
Ensembl Gene ENSMUSG00000049649
Encoded Proteins
G-protein coupled receptor 3
G-protein coupled receptor 3
G-protein coupled receptor 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000181773:
This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer's disease. [provided by RefSeq, Oct 2012]
This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer\'s disease. [provided by RefSeq, Oct 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:133209340-133212536
Strand Reverse strand
Band D2.3
Transcripts
ENSMUST00000052090 ENSMUSP00000062083
ENSMUST00000105911 ENSMUSP00000101531
ENSMUST00000151025 ENSMUSP00000116032
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0005515 protein binding
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0030816 positive regulation of cAMP metabolic process
GO:0040020 regulation of meiosis
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL B1AUM8
UniProt Splice Variant
Entrez Gene 14748
UniGene Mm.4721
RefSeq NM_008154
OMIM
CCDS CCDS18743
HPRD
IMGT
MGI ID MGI:101908
MGI Symbol Gpr3
EMBL AL671858
GenPept
RNA Seq Atlas 14748