InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Kif18a

Summary

InnateDB Gene

IDBG-195464.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Kif18a

Gene Name

kinesin family member 18A

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000027115

Encoded Proteins

IDBP-195466

kinesin family member 18A

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000121621:
KIF18A is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that use hydrolysis of ATP to produce force and movement along microtubules (Luboshits and Benayahu, 2005 [PubMed 15878648]).[supplied by OMIM, Aug 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:109280738-109341747

Strand

Forward strand

Band

Transcripts

ENSMUST00000028527	ENSMUSP00000028527
ENSMUST00000130137
ENSMUST00000151395
ENSMUST00000144924
ENSMUST00000152751
ENSMUST00000162515

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003777	microtubule motor activity
GO:0003779	actin binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008017	microtubule binding
GO:0008574	plus-end-directed microtubule motor activity
GO:0043130	ubiquitin binding
GO:0051010	microtubule plus-end binding
GO:0070463	tubulin-dependent ATPase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0007018	microtubule-based movement
GO:0007019	microtubule depolymerization
GO:0007080	mitotic metaphase plate congression
GO:0008152	metabolic process
GO:0015031	protein transport

Cellular Component

GO:0001726	ruffle
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005815	microtubule organizing center
GO:0005828	kinetochore microtubule
GO:0005871	kinesin complex
GO:0005901	caveola
GO:0015630	microtubule cytoskeleton