Version 5.4
Mus musculus Gene: Scimp
Summary
InnateDB Gene IDBG-195523.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Scimp
Gene Name SLP adaptor and CSK interacting membrane protein
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000057135
Encoded Proteins
IDBP-195525
RIKEN cDNA A430084P05 gene
IDBP-264333
RIKEN cDNA A430084P05 gene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000161929:
This gene encodes a transmembrane adaptor protein that is expressed in antigen-presenting cells and is localized in the immunologic synapse. The encoded protein is involved in major histocompatibility complex class II signal transduction and immune synapse formation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:70790932-70812586
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000074572 ENSMUSP00000074157
ENSMUST00000108534 ENSMUSP00000104174
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0070374 positive regulation of ERK1 and ERK2 cascade
Cellular Component
GO:0001772 immunological synapse
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031256 leading edge membrane
GO:0031259 uropod membrane
GO:0097197 tetraspanin-enriched microdomain
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000161929
View Gene Order
ENSBTAG00000035975
Not yet available
Cross-References
SwissProt Q3UU41
TrEMBL F8WHN0
UniProt Splice Variant
Entrez Gene 327957
UniGene Mm.164325
RefSeq NM_001045526 XM_006533561 XM_006533562 XM_006537170 XM_006537171
OMIM
CCDS CCDS24967
HPRD
IMGT
MGI ID MGI:3610314
MGI Symbol Scimp
EMBL AK138818 AL596117 BC147177 BC147178 CR933735
GenPept AAI47178 AAI47179 BAE23788 CAI25187 CAM28154
RNA Seq Atlas 327957

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca