InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Nr5a2

Summary

InnateDB Gene

IDBG-195757.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nr5a2

Gene Name

nuclear receptor subfamily 5, group A, member 2

Synonyms

AU020803; D1Ertd308e; Ftf; LRH-1; UF2-H3B

Species

Mus musculus

Ensembl Gene

ENSMUSG00000026398

Encoded Proteins

IDBP-195759

nuclear receptor subfamily 5, group A, member 2

IDBP-620014

nuclear receptor subfamily 5, group A, member 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116833:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:136843584-136960427

Strand

Reverse strand

Band

Transcripts

ENSMUST00000027649	ENSMUSP00000027649
ENSMUST00000168126	ENSMUSP00000129071

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	20 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003707	steroid hormone receptor activity
GO:0005515	protein binding
GO:0005543	phospholipid binding
GO:0008270	zinc ion binding
GO:0043565	sequence-specific DNA binding
GO:0044212	transcription regulatory region DNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0008206	bile acid metabolic process
GO:0031018	endocrine pancreas development
GO:0042127	regulation of cell proliferation
GO:0042632	cholesterol homeostasis
GO:0043401	steroid hormone mediated signaling pathway
GO:0045070	positive regulation of viral genome replication
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000116833

View Gene Order

ENSBTAG00000009265

Not yet available

Pathways

NETPATH

REACTOME

REACT_234105

Nuclear Receptor transcription pathway pathway

REACT_208465

Regulation of gene expression in early pancreatic precursor cells pathway

REACT_233572

Gene Expression pathway

REACT_188576

Developmental Biology pathway

REACT_205507

Regulation of beta-cell development pathway

REACT_206529

Generic Transcription Pathway pathway

KEGG

mmu04950

Maturity onset diabetes of the young pathway

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

KEGG

hsa04950

Maturity onset diabetes of the young pathway

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.16794

RefSeq

NM_001159769 NM_030676 XM_006529620 XM_006529621 XM_006529622

OMIM

CCDS

CCDS15328 CCDS48382

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas