Version 5.4
| Mus musculus Gene: Atp6v1g3 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-195994.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Atp6v1g3 | ||||||||
| Gene Name | ATPase, H+ transporting, lysosomal V1 subunit G3 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000026394 | ||||||||
| Encoded Proteins |
ATPase, H+ transporting, lysosomal V1 subunit G3
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151418:
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 1:138273738-138289460 | ||||||||
| Strand | Forward strand | ||||||||
| Band | E4 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Disease pathway
Signaling by Insulin receptor pathway
Transferrin endocytosis and recycling pathway
Phagosomal maturation (early endosomal stage) pathway
Latent infection of Homo sapiens with Mycobacterium tuberculosis pathway
Iron uptake and transport pathway
Transmembrane transport of small molecules pathway
Insulin receptor recycling pathway
Signal Transduction pathway
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| KEGG |
Oxidative phosphorylation pathway
Phagosome pathway
Collecting duct acid secretion pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Transferrin endocytosis and recycling pathway
Iron uptake and transport pathway
Insulin receptor recycling pathway
Signaling by Insulin receptor pathway
Phagosomal maturation (early endosomal stage) pathway
Transmembrane transport of small molecules pathway
Signal Transduction pathway
Latent infection of Homo sapiens with Mycobacterium tuberculosis pathway
Disease pathway
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| KEGG |
Vibrio cholerae infection pathway
Epithelial cell signaling in Helicobacter pylori infection pathway
Oxidative phosphorylation pathway
Collecting duct acid secretion pathway
Phagosome pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8BMC1 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 338375 | ||||||||
| UniGene | Mm.114424 | ||||||||
| RefSeq | NM_177397 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS15331 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:2450548 | ||||||||
| MGI Symbol | Atp6v1g3 | ||||||||
| EMBL | AB088359 AK032887 BC107267 BC107268 | ||||||||
| GenPept | AAI07268 AAI07269 BAC28072 BAC57952 | ||||||||
| RNA Seq Atlas | 338375 | ||||||||