Bos taurus Gene: BT.99275
Summary
InnateDB Gene IDBG-638667.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.99275
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019890
Encoded Proteins
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151418:
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:79333029-79353972
Strand Reverse strand
Band
Transcripts
ENSBTAT00000026498 ENSBTAP00000026498
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism
GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
GO:0051117 ATPase binding
Biological Process
GO:0015992 proton transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016471 vacuolar proton-transporting V-type ATPase complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Transferrin endocytosis and recycling pathway
Iron uptake and transport pathway
Insulin receptor recycling pathway
Signaling by Insulin receptor pathway
Phagosomal maturation (early endosomal stage) pathway
Transmembrane transport of small molecules pathway
Signal Transduction pathway
Latent infection of Homo sapiens with Mycobacterium tuberculosis pathway
Disease pathway
Disease pathway
Signaling by Insulin receptor pathway
Transferrin endocytosis and recycling pathway
Phagosomal maturation (early endosomal stage) pathway
Latent infection of Homo sapiens with Mycobacterium tuberculosis pathway
Iron uptake and transport pathway
Transmembrane transport of small molecules pathway
Insulin receptor recycling pathway
Signal Transduction pathway
KEGG
Vibrio cholerae infection pathway
Epithelial cell signaling in Helicobacter pylori infection pathway
Oxidative phosphorylation pathway
Collecting duct acid secretion pathway
Phagosome pathway
Oxidative phosphorylation pathway
Phagosome pathway
Collecting duct acid secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BMV6
UniProt Splice Variant
Entrez Gene 613925
UniGene Bt.99275
RefSeq XM_002694234 XM_865147
HUGO HGNC:18265
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02043920
GenPept
RNA Seq Atlas 613925