Version 5.4
Mus musculus Gene: Dapp1
Summary
InnateDB Gene IDBG-196059.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dapp1
Gene Name dual adaptor for phosphotyrosine and 3-phosphoinositides 1
Synonyms Bam32
Species Mus musculus
Ensembl Gene ENSMUSG00000028159
Encoded Proteins
IDBP-196061
dual adaptor for phosphotyrosine and 3-phosphoinositides 1
IDBP-541480
dual adaptor for phosphotyrosine and 3-phosphoinositides 1
IDBP-790173
dual adaptor for phosphotyrosine and 3-phosphoinositides 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000070190:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:137931007-137981545
Strand Reverse strand
Band G3
Transcripts
ENSMUST00000029806 ENSMUSP00000029806
ENSMUST00000136613 ENSMUSP00000119634
ENSMUST00000124827
ENSMUST00000154716
ENSMUST00000184222 ENSMUSP00000138991
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0035014 phosphatidylinositol 3-kinase regulator activity
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding
Biological Process
GO:0043551 regulation of phosphatidylinositol 3-kinase activity
Cellular Component
GO:0005886 plasma membrane
GO:0005942 phosphatidylinositol 3-kinase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000070190
View Gene Order
ENSBTAG00000007921
Not yet available
Pathways
NETPATH
REACTOME
REACT_188199
Signaling by the B Cell Receptor (BCR) pathway
REACT_188194
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers pathway
REACT_230745
Immune System pathway
REACT_229531
Adaptive Immune System pathway
KEGG
mmu04662
B cell receptor signaling pathway pathway
INOH
INOH website
B cell receptor signaling pathway
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
NetPath_12
BCR pathway
NetPath_24
TSLP pathway
REACTOME
REACT_118700
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_118773
Signaling by the B Cell Receptor (BCR) pathway
KEGG
hsa04662
B cell receptor signaling pathway pathway
INOH
INOH website
B cell receptor signaling pathway
PID NCI
pi3kcipathway
Class I PI3K signaling events
bcr_5pathway
BCR signaling pathway
Cross-References
SwissProt
TrEMBL Q3TEK6
UniProt Splice Variant
Entrez Gene 26377
UniGene Mm.254835 Mm.470427
RefSeq NM_011932
OMIM
CCDS CCDS17864
HPRD
IMGT
MGI ID MGI:1347063
MGI Symbol Dapp1
EMBL AC146607 AK169584
GenPept BAE41242
RNA Seq Atlas 26377

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca